May 22 is the 142nd day of the year (143rd in leap years). There are 223 days remaining.
- 1942 — Ted Kaczynski is born.
- 1942 — Eddie Leonski is apprehended.
- 1951 — Kenneth Bianchi is born.
- 1955 — Lam Kor-wan is born.
- 1961 — Carol Christensen (victim) is born.
- 1967 — Todd Alan Reed is born.
- 1972 — Irina Gaidamachuk is born.
- 1980 — Richard Cottingham is apprehended.
- 1981 — Nathaniel Cater is murdered by Wayne Williams.
- 1983 — Martina Theresa Authorlee is murdered by Gary Ridgway.
- 1983 — Charles Gunnar is murdered by Leonard Lake and Charles Ng.
- 1983 — Juan David Ortiz is born.
- 1985 — Jiří Straka is apprehended.
- 1990 — Arthur Gatter is apprehended.
- 1994 — Ivan Milat is apprehended.
- 1995 — Boris Bogdanov died.
- 1999 — Carlos Yadiel Baez-Nieves is born.
- 2001 — Zhang Jing is murdered by Gao Chengyong.
- 2013 — Mark Smich is apprehended.
- 2020 — Roy Melanson died.