May 16 is the 136th day of the year (137th in leap years). There are 229 days remaining.
- 1861 — H. H. Holmes is born.
- 1878 — Lydia Sherman died.
- 1944 — Henry Gein is allegedly murdered by Ed Gein (suspected victim).
- 1955 — John Benjamin Kennedy Jr. is born.
- 1963 — David Bruce is born.
- 1968 — Boris Gusakov is apprehended.
- 1974 — Themba Sukude is born.
- 1978 — Vera Millward is murdered by Peter Sutcliffe.
- 1979 — Kampatimar Shankariya died.
- 1981 — Michael Joseph Albanese is murdered by Charles Albanese.
- 1983 — Edmund Kolanowski is apprehended.
- 1984 — Tammy Rothganger is murdered by Martin Priest.
- 1990 — Joanna Parrish is murdered by Michel Fourniret.
- 1996 — Michael Allen Lyons is murdered by Robert Boyd Rhoades.
- 1997 — Valdek Laas is apprehended.
- 2000 — Céline Saison is murdered by Michel Fourniret.
- 2005 — Gayno Smith died.
- 2021 — Ali Akbar Khorramdin and Iran Mousavi Sani are apprehended.