April 27 is the 117th day of the year (118th in leap years), with 248 days remaining.
- 1896 — Carl Feigenbaum died.
- 1944 — James Antonio Barnes is born.
- 1964 — James Greenfield is born.
- 1968 — Juan Rodriguez Chavez is born.
- 1970 — Levan Aroyan is born.
- 1973 — Timothy Joseph McGhee is born.
- 1982 — Jean McPhaul is allegedly murdered by Mike DeBardeleben (suspected victim).
- 1985 — Marine Wallace Hedge is murdered by Dennis Rader.
- 1991 — The "Bowraville Killers"'s 2nd known victim, Evelyn Greenup, is found.
- 1992 — Michael McCown is murdered by the "I-70 Killer".
- 1994 — Timothy Spencer died.
- 2007 — Annick Van Uytsel is murdered by Ronald Janssen (possibly killed on April 28).
- 2007 — Timothy Barnwell is murdered by Samuel Cooper.
- 2009 — Honoré Zanchi is apprehended.
- 2011 — Gary Srery died.
- 2017 — Reginald Kimbro is apprehended.